Publications, Patents and Examples
Strain development
Microbiome
Product Development
Functional Analyzes
Regulatory
Human Trial
HUMIPLATE ® For Microbiome Modulation Properties Of A Plant Extract (Menthacarin).
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Menthacarin, a proprietary combination of peppermint and caraway oil, alters cultured human fecal microbiota composition, resulting in increased SCFA production. Lehner M.D., Ulsemer P. and Christochowitz S. (2025). Front. Pharmacol. 16:1569052. doi: 10.3389/fphar.2025.1569052
MicroSIS - Isolation And Further Development Of
Commensal Bacterial Strains Naturally Neutralizing The
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Exploring the pathogen binding potential within the human gut microbiome.Human Microbiome Journal. Kawe Toutounian, Marie Luise Heinig, Peter Götz and Philippe Ulsemer. https://doi.org/10.1016/j.humic.2020.100075.
MicroSIS - Human Trial: Safety Of A Next Generation
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Safety and tolerance of Bacteroides xylanisolvens DSM 23964 in healthy adults. Beneficial Microbes, 3(2), 99-112. Ulsemer P., Toutounian K., Kressel G., Schmidt J., Karsten U., Hahn A., Goletz S. https://doi.org/10.3920/BM2011.0051
MicroSIS - Human Trial - Anti-Cancer Properties Of A
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Impact of oral consumption of heat-treated Bacteroides xylanisolvens DSM 23964 on the level of natural TFα-specific antibodies in human adults. Beneficial Microbes, 7(4), 485-500. Ulsemer P., Toutounian K., Kressel G., Goletz C., Schmidt J., Karsten U., Hahn A., Goletz S. https://doi.org/10.3920/BM2015.0143
MicroSIS - Anti-Cancer Properties Of A Commensal
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Specific humoral immune response to the Thomsen-Friedenreich tumor antigen (CD176) in mice after vaccination with the commensal bacterium Bacteroides ovatus D-6. Cancer Immunol Immunother. May;62(5):875-87. Ulsemer P., Henderson G., Toutounian K., Löffler A., Schmidt J., Karsten U., Blaut M., Goletz S. doi: 10.1007/s00262-013-1394-x.
Regulatory: Safety Assessment Of A Next Generation
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Safety assessment of the commensal strain Bacteroides xylanisolvens DSM 23964. Regul Toxicol Pharmacol. Mar;62(2):336-46. Ulsemer P., Toutounian K., Schmidt J., Leuschner J., Karsten U., Goletz S. doi: 10.1016/j.yrtph.2011.10.014.
Regulatory: Safety Assessment Of A Next Generation
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Preliminary safety evaluation of a new Bacteroides xylanisolvens isolate. Appl Environ Microbiol. Ulsemer P., Toutounian K., Schmidt J., Karsten U., Goletz S. doi: 10.1128/AEM.06641-11.
MicroSIS - Isolation and further Development of Commesal
Bacteria Naturally Expressing Tumor Associated Carbohydrate
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Occurrence of the human tumor-specific antigen structure Galβ1-3GalNAcα- (Thomsen-Friedenreich) and related structures on gut bacteria: prevalence, immunochemical analysis and structural confirmation. Glycobiology. (10):1277-89. Henderson G., Ulsemer P., Schöber U., Löffler A., Alpert C.A., Zimmermann-Kordmann M., Reutter W., Karsten U., Goletz S., Blaut M. doi: 10.1093/glycob/cwr058.
Use of Commensal Bacteria As New Anti-Infection Agent
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Natural non-pathogenic microorganisms capable of associating glycolipids or lipopeptides and use thereof. Applicant: ACARYON GMBH - Inventors: Philippe Ulsemer, Kawe Toutounian
Use of Commensal Bacteria As New Cancer Prevention
Agent
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Microorganisms carrying a tumor antigen. Abstract: The present invention pertains to microorganisms of the species Bacteroides xylanisolvens expressing a core-1 antigen on their surface. These microorganisms are in particular useful for the prophylaxis and treatment of core-1 positive diseases.. Inventors: Steffen Goletz, Philippe Ulsemer, Kawe Toutounian
New Fermentation Process For Industrial Production of
Anaerobic Microorganism
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Fermentation process:.Abstract: The present disclosure relates in one embodiment to a method of producing a fermented food .... Inventors: Steffen Goletz, Philippe Ulsemer
Carbohydrate Specific Cellular Immunity Inducing
Microorganisms And Fractions Thereof.
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Abstract: The present invention relates to the field of prevention and treatment of disorders associated with the occurrence of certain carbohydrate epitopes. Inventors: Steffen Goletz, Philippe Ulsemer, Anja Löffler
Microorganisms Of The Species Bacteroides Xylanisolvens
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The present invention pertains to food products comprising microorganisms of the species Bacteroides xylanisolvens. Inventors: Steffen Goletz, Philippe Ulsemer, Kawe Toutounian
Microorganisms or fractions thereof capable of
activating cellular immunity against carbohydrates.
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Abstract: The present invention relates to the field of prevention and treatment of tumors and gastrointestinal disorders. Inventors: Steffen Goletz, Phillippe Ulsemer, Anja Löffler
