HUMIPLATE
MICROBIOME MODULATION
Next-Generation Fully Integrated
ex vivo High Throughput Microbiome Platform
To provide comprehensive insights into the microbiome-modulating health properties of your product(s).
High-throughput (up to 150 wells at once)
Time and cost effective
Microbiome fidelity for high translatability
Integrated with metabolomics and functional cell assays
Real native microbiomes
More than a cultivation system,
HUMIPLATE is a fully integrated
ex-vivo microbiome cultivation platform
providing unique insights and flexibility
Function
The broadest cellular functional analysis platform in the market
Metabolome
Up to 240 Metabolites per sample at once
Metagenome
NGS
(16S rRNA, Shotgun etc.)
PROPRIETARY SCIENTIFIC DATABASE
Compiles scientific evidence on microbiome-related health effects
SCIENTIFIC RELEVANCE INDEX
A proprietary unified metric integrating scientific community consensus.
PROPRIETARY CLINICAL DATABASE
Integrates clinical evidence on microbiome-disease associations
DISEASE IMPACT SCORE
Compares product-impact on biomarker to estimate potential impact on the disease.
BIOINFORMATICS
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All canonical bioinformatic tools
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Unique at ACARYON
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Disease impact score
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Proprietary BioRelevance framework
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Abundance stratified acceptance framework
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Metabolite production potential
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Microbiome-metabolite correlation
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Composition-function corelation
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and more
HUMILATE was designed to deliver highly translatable microbiome data by simulating key in vivo-like conditions in a scalable ex vivo format. The platform preserves inoculum integrity over time, maintaining microbiome composition at the genus level, sustaining the viability of sensitive species, and retaining overall community diversity throughout cultivation
More than a cultivation system, HUMIPLATE is a fully integrated microbiome discovery platform providing high customer flexibility.
It combines ex vivo cultivation with compositional profiling, metabolite analysis, functional characterization, and the full portfolio of ACA-Health assays.
Customers can tailor the process to their specific needs: starting with composition analysis and expanding later to functional characterization on selected samples, or beginning with functional analyses and adding compositional profiling afterward.
HUMIPLATE also gives customers the option to receive supernatants and other cultivation-derived fractions for complementary downstream investigations.
Supported by advanced, biologically relevant bioinformatics, HUMIPLATE turns complex microbiome datasets into clear, actionable insights on product-driven microbiome modulation and potential health impact.
High translational relevance through simulation of in vivo-like microbiome conditions
Demonstrated inoculum integrity with preservation of composition, viability, and diversity
Integrated functional insight from metabolomics to broader functional analyzes
ACA-Health integration for comprehensive, end-to-end microbiome assessment
Unique bioinformatics tools designed to deliver biologically meaningful interpretation, not just data
HUMIPLATE
High Throughput
Test Multiple Conditions & Concentrations Simultaneously (up to 150 wells at once)
Gain exclusive insights into the concentration-dependent effects of your product. Easily compare different formulations or test under multiple conditions - all in one streamlined analysis.
Native Microbiomes
Tailored to Your Needs
Run your study on a single microbiome for quick screening or test across multiple microbiomes with specific characteristics (e.g., sex, age, BMI, health status etc.).
Customer's own microbiome samples (fresh or froozen) may be used!
Inoculum Fidelity
The Key to High-Quality, Translational Outcomes
HUMIPLATE uniquely maintains native gut microbial integrity to the genus level, enabling biologically meaningful insights and true translational relevance.
Microbiome Composition
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From the isolation of pellets to delivering of compositional data, we take care of all steps.
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At the end of the cultivation, pellets and supernatants are isolated.
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Pellets are used for compositional analyses.
Metabolite Profiling
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At the end of the cultivation, pellets and supernatants are isollated.
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Our of the supernatants, metabolites can be quantified.
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From quantification of single SCFA up to quantification of 240 relevant metabolites.
Functional Profiling
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The Broadest Analytical Platform on The Market allows us to go beyond conposition and to evaluate key functional properties such as anti-inflammatory effects, immune modulation, antimicrobial activity, and more.
Navigate integrated data complexity with confidence
Proprietary Tools
Our AI-driven analytical tools, powered by proprietary microbiome databases, provide unique and biologically relevant insights to guide product development and differentiation.
No black box algorithms! Our tools are built by experts on biologically meaningful foundations, delivering scientifically sound results.
PROPRIETARY SCIENTIFIC DATABASE
Compiles scientific evidence on microbiome-related health effects
SCIENTIFIC RELEVANCE INDEX
A proprietary unified metric integrating scientific community consensus.
PROPRIETARY CLINICAL DATABASE
Integrates clinical evidence on microbiome-disease associations
DISEASE IMPACT SCORE
Compares product-impact on biomarker to estimate potential impact on the disease.
BIOINFORMATICS
-
All canonical bioinformatic tools
-
Unique at ACARYON
-
Disease impact score
-
Proprietary BioRelevance framework
-
Abundance stratified acceptance framework
-
Metabolite production potential
-
Microbiome-metabolite correlation
-
Composition-function corelation
-
and more
