With two decades of experience in the probiotic field, we draw on our extensive background to develop a broad range of services. We support our customers in analysing, screening and/or improving the properties of their products, in speeding up the development processes and improving quality controls.
What Can We Help With?
Pre- and Probiotic Analytical Services
Discover the broadest range of probiotic specific assays dedicated to support customers in analysing, screening and/or improving the properties of their products.
General Probiotic Properties
Taxonomy and Strain Characterization
•Taxonomy analysis including biochemical, MALDI-TOF, RAPD profile etc.
•Characterization (antibiotics resistance, virulence factors, presence of plasmids etc.)
Basic Probiotic Properties
•Resistance to simulated gastric and gut conditions
•Binding to cells (intestinal cells, skin cells etc.)
•Binding to extracellular matrix
•Quantification of cells and
•Analysis of the ability of probiotics to produce compounds directly killing or preventing the growth of the pathogens and the ability to growth at the expense of the pathogen
•Probiotic may avoid bacterial infections by avoiding the binding of pathogens to host cells.
•We analyse, screen and optimize the bacterial exclusion properties of probiotics
•Probiotics may inhibit viral infections by avoiding the binding of the virus to host cells.
•We analyze, screen and optimize the virus exclusion properties and the virus binding properties of probiotics.
•Pathogens may produce toxins. Probiotics may inhibit infections by avoiding the binding of such toxins to host cells.
•We analyse, screen and optimize the toxin exclusion properties of probiotics
•Destabilization of the gut barrier is involved in many clinical conditions including infections, cancer, obesity, diabetes etc.
•We analyse, screen and optimize the gut barrier promoting properties of products.
•Probiotics can modulate the immune response via the local production of immune factors (i.e. cytokines).
•We analyze the ability of probiotics or products to modulate the expression of key cytokines.
In vitro Microbiome Analysis
•Dysbiosis of the gut microbiota is at the origin of many intestinal and extra-intestinal disorders.
•We analysis the effect of probiotics on human microbiome by means of NGS, real Time PCR or Agar Count.
To support and speed up our client's development process, we develop customized assays (cell culture assays, ELISA assays, screening assays etc.)
We further ensure the transfer and integration of these methods in the customer’s development process or in the quality control process.
Fermentation and Production Processes
Screening of strains for optimal fermentation or production process
Development of customized fermentation process for aerobic and anaerobic strains
Medium optimization: to increase yield, to improve functional properties, for regulatory purposes
Development of quality control assays (i.e. taxonomy, contaminations, strain properties like epitopes, polysaccharide expression, etc.)