Unique Strain Development

Microbial Carbohydrates for Next Generation Probiotics

Microbial carbohydrates are:

Consequently, microorganisms are strongly relying on carbohydrates and carbohydrate binding structures for specific regulation of their environment and of the microbiome host axis.

Microbial carbohydrates are essential for many processes including:

Take Advantage Of Microbial Carbohydrates For The Development Of Innovative Probiotics

What Can Help You With?

Discover unexpected properties of your strain(s)

You can rely on our 20 years of experience in the field of microbial carbohydrate and microbiome applications.

Improve your strains properties

We analysed yet more than 10.000 strains for carbohydrate related properties.

Develop strain(s) with unique properties

With our MicroSIS-Platform we can screen the microbiome for microorganisms expressing specific carbohydrate structures.

Microbial Carbohydrate For Next Generation Probiotics

discover some examples

Specific Anti-Infection Properties

Bacterial strains which naturally express a carbohydrate structure mimicking receptor for a pathogen, a virus or a toxin can specifically displaces the pathogen, virus or toxin and potentially avoid the related disease.

Example: Binding and neutralizing the cholera toxin. Toutounian et. al. Human Microbiome Journal, Volume 18, December 2020

Example: Microbial carbohydrate antigen inducing an anti-cancer immune response. Ulsemer et. al. Beneficial Microbes. 2016 Sep;7(4):485-500.

Specific Immune Modulation

Bacterial strains naturally expressing or secreting specific carbohydrate structures (antigen or immune stimulatory) can stimulate the immune system.

Specific Promotion Or Inhibition Of Growth

Bacterial strains naturally expressing or secreting specific carbohydrate structures can promote or inhibit the growth of other species.